PENGARUH GLIBENKLAMID KOMBINASI MINYAK BUAH MERAH (Pandanus conoideus Lam.) TERHADAP TINGKAT KERUSAKAN KORPUSKULUM MALPHIGI RENALIS TIKUS JANTAN GALUR WISTAR DIABETES

Simple item page
dc.contributor.authorPerkasa, Hendra
dc.date.accessioned2012-11-06T03:45:40Z
dc.date.available2012-11-06T03:45:40Z
dc.date.issued2012-11-05
dc.description.abstractABSTRACT Diabetes mellitus is one of a metabolism disorder with characteristic of the hyperglycemia caused by abnormal insulin secretion resistance, insulin metabolism, or both. Diabetes mellitus complications in kidney is related with hyperglycemia cause increasing oxidative stress and distrubance antioxidant defence. Pandanus conoideus Lam. oil containing β-carotene, β-cryptoxanthin and α-tocopherol can reduce oxidative stress. This study aimed to determine the effect of glibenclamide combination P. conoideus Lam. oil on histochemical changes corpusculum malphigi diabetes. Wistar rats were divided into four groups; normal group, DM group, diabetic group given glibenclamide and diabetic groups were given glibenclamide combination Pandanus conoideus Lam. oil. The results showed significant differences (p <0.05) on histological glomerulosclerosis, capillary dilatation, mesangial matrix expansion and mesangiolysis. Based on this study; it can be concluded that administration of glibenclamide combination Pandanus conoideus Lam. oil can prevent the progression of Corpusculum malphigi damage in diabetic ratsen_US
dc.description.sponsorshipWinarto, M. Yulis Hamidyen_US
dc.identifier.otheryeni
dc.identifier.urihttp://hdl.handle.net/123456789/367
dc.language.isootheren_US
dc.subjectPandanus conoideus Lam. oilen_US
dc.subjectdiabetes mellitusen_US
dc.subjecthyperglicemiaen_US
dc.subjectantioxidanten_US
dc.subjectcorpusculum malphigien_US
dc.titlePENGARUH GLIBENKLAMID KOMBINASI MINYAK BUAH MERAH (Pandanus conoideus Lam.) TERHADAP TINGKAT KERUSAKAN KORPUSKULUM MALPHIGI RENALIS TIKUS JANTAN GALUR WISTAR DIABETESen_US
dc.typeArticleen_US

Files

Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
hendra perkasa.pdf
Size:
678.15 KB
Format:
Adobe Portable Document Format
Description:
artikel publikasi
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

Education of Medical