SINTESIS DAN UJI TOKSISITAS SENYAWA ANALOG 3’, 4’-DIMETOKSI KALKON
| dc.contributor.author | Novianti, S | |
| dc.date.accessioned | 2015-03-23T03:29:16Z | |
| dc.date.available | 2015-03-23T03:29:16Z | |
| dc.date.issued | 2015-03-23 | |
| dc.description.abstract | Chalcones belong to important class of flavonoid compounds. They have also been reported to have anticancer, antimicrobial, antifungal, antioxidant, and cytotoxic activities. In this research, an analogous chalcone of (E)-3-(4-clorophenyl)-1-(3’,4’- dimetoxyphenyl) prop- 2-en-1-on was synthesized using microwave iradiation and natrium hidroxide as catalyst. The compound showed a good yield, and then was characterized by UV spectroscopy, IR, 1H-NMR, and Mass Spectroscopy. Its toxicity has been identified using Brine Shrimp Lethality Test (BSLT) method on Artemia salina Leach. The result showed that it had a good toxicity activity with LC50 = 2.24 μg/ mL and potential as anticancer | en_US |
| dc.description.sponsorship | N. Balatif2, A. Zamri2, | en_US |
| dc.identifier.other | wahyu ari yeni | |
| dc.identifier.uri | http://repository.unri.ac.id/xmlui/handle/123456789/6885 | |
| dc.language.iso | en | en_US |
| dc.subject | 3’, 4’ | en_US |
| dc.subject | dimetoxyacetophenone | en_US |
| dc.subject | BSLT | en_US |
| dc.subject | chalcones, toxicity | en_US |
| dc.title | SINTESIS DAN UJI TOKSISITAS SENYAWA ANALOG 3’, 4’-DIMETOKSI KALKON | en_US |
| dc.type | UR-Student Paper Diploma | en_US |
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