SINTESIS DAN UJI TOKSISITAS SENYAWA (1-(NAFTALEN-2-IL) ETILIDEN)HIDRAZIN

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dc.contributor.authorSeptiani, Vivin
dc.contributor.supervisorJasril, Jasril
dc.date.accessioned2021-10-19T03:56:05Z
dc.date.available2021-10-19T03:56:05Z
dc.date.issued2021-03
dc.description.abstractHydrazone is an organic compound that has a basic structure (R1R2C=N-NR3R4). Azomethine (-NHN=CH) is the active group of the hydrazone compound, which makes this compound has a variety biological activities. In this research, the synthesis of the hydrazone compound (1-(naphtalene-2-il)ethyliden)hydrazine (IHK-AN2) obtained from the condensation reaction between 2-acetylnaphtalene and hydrazine hydrate catalyzed by acetic acid. The compound was synthesized using microwave irradiation method with 180 watt. The purity of the compound was determined by TLC, melting point measurement and HPLC analysis. The compound was analyzed by UV and FTIR spectrophotometer. Synthesis of hydrazone in this research was concluded with a yield 85,86%. The toxicity of the IHK-AN2 compound was evaluated by BSLT method. LC50 value of the compound was >1000 μg/mL. From the data above was concluded that the IHK-AN2 compound was not toxic.en_US
dc.description.sponsorshipDosen Bidang Kimia Organik Jurusan Kimia Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Riauen_US
dc.identifier.otherwahyu sari yeni
dc.identifier.urihttps://repository.unri.ac.id/handle/123456789/10285
dc.language.isoenen_US
dc.subjectBSLTen_US
dc.subjecthydrazoneen_US
dc.subjecttoxicityen_US
dc.titleSINTESIS DAN UJI TOKSISITAS SENYAWA (1-(NAFTALEN-2-IL) ETILIDEN)HIDRAZINen_US
dc.typeArticleen_US

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