SINTESIS ANALOG KURKUMIN TURUNAN 1-BENZIL 4-PIPERIDINON MENGGUNAKAN KATALIS BASA DAN UJI AKTIVITAS SEBAGAI ANTIBAKTERI
| dc.contributor.author | Wahyuni, S. | |
| dc.contributor.author | Eryanti, Y. | |
| dc.contributor.author | Zamri, A. | |
| dc.contributor.author | Jasril | |
| dc.date.accessioned | 2014-03-27T06:24:07Z | |
| dc.date.available | 2014-03-27T06:24:07Z | |
| dc.date.issued | 2014-03-27 | |
| dc.description.abstract | Curcumin is one of secondary metabolites with phenolic group which was known to have various biological activities such as antimicroba, anticancer, antioxidant, antitumor and anti-inflammatory activities. In this research, curcumin analog of 1-benzil-4- piperidone derivative was synthesized using microwave irradiation with catalyst NaOH. The rendement (YN2) resulted 99.39%. All compounds were characterized using UV spectrophotometer, IR spectrophotometer, 1 H NMR, and 13 C NMR spectrometers. The antibacterial activity was evaluated using the agar diffusion method. Antibacterial activity test was carried out at concentrations of 20, 30, 40, 50 , and 60 mg/disc against Gram positive bacteria (Staphylococcus aureus and Bacillus subtilis) and Gram negative bacteria (Escherichia coli and Salmonella enteritidis). YN 2 compounds obtained showed different antibacterial activity against different bacteria. | en_US |
| dc.description.sponsorship | Eryanti, Y., Zamri, A., Jasril | en_US |
| dc.identifier.other | Rangga Dwijunanda Putra | |
| dc.identifier.uri | http://repository.unri.ac.id/xmlui/handle/123456789/5940 | |
| dc.language.iso | other | en_US |
| dc.subject | Antibacterial | en_US |
| dc.subject | curcumin | en_US |
| dc.subject | irradiation microwave | en_US |
| dc.title | SINTESIS ANALOG KURKUMIN TURUNAN 1-BENZIL 4-PIPERIDINON MENGGUNAKAN KATALIS BASA DAN UJI AKTIVITAS SEBAGAI ANTIBAKTERI | en_US |
| dc.type | Other | en_US |