SINTESIS DAN UJI TOKSISITAS SENYAWA 1-(NAFTALEN-1- ILMETILEN)-2-FENILHIDRAZIN

Simple item page
dc.contributor.authorFauza, Sarfatika Nurul
dc.contributor.supervisorJasril, Jasril
dc.date.accessioned2021-08-24T04:57:17Z
dc.date.available2021-08-24T04:57:17Z
dc.date.issued2020-10
dc.description.abstractHydrazone is an organic compound that has a variety of biological activities such as antioxidant and anticancer. The active group of hydrazone compound the azomethine group (-NHN=CH-) makes this compound as an important compound in the development of new drugs. Hence, in this study, the synthesis of hydrazone 1-(naphthalene-1-ylmetilen)-2-phenylhydrazine (IFA-ND1) was obtained from the condensation reaction between 1-naphthalene and phenylhydrazine catalyzed by acetic acid. This compound was synthesized compound by microwave irradiation method at 180 Watt. The purity of the compound is determined by using thin layer chromatography and melting point. The structure of the synthesized compound was characterized by the spectrum of UV and FTIR. The bioactivity of the IFA-ND1 compound was evaluated with its toxicity properties by BSLT method with a value of LC50 = 1.455 μg/mL. This suggests that the IFA-ND1 compound is a potential compound with toxic propertiesen_US
dc.description.sponsorship2Dosen Bidang Kimia Organik Jurusan Kimia Fakultas Matematika dan Ilmu Pengetahuan Alamen_US
dc.identifier.otherwahyu sari yeni
dc.identifier.urihttps://repository.unri.ac.id/handle/123456789/10151
dc.language.isoenen_US
dc.subjectazomethineen_US
dc.subjecthydrazoneen_US
dc.subjecttoxicityen_US
dc.titleSINTESIS DAN UJI TOKSISITAS SENYAWA 1-(NAFTALEN-1- ILMETILEN)-2-FENILHIDRAZINen_US
dc.typeArticleen_US

Files

Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
sarfatika nurul fauza_compressed.pdf
Size:
158.21 KB
Format:
Unknown data format
Description:
artikel
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

Chemical