SINTESISDANUJITOKSISITASSENYAWAANALOG 3’,4’-DIMETOKSIKALKON
| dc.contributor.author | Novianti, S. | |
| dc.contributor.author | Balatif, N. | |
| dc.contributor.author | Zamri, A. | |
| dc.date.accessioned | 2014-03-27T06:12:52Z | |
| dc.date.available | 2014-03-27T06:12:52Z | |
| dc.date.issued | 2014-03-27 | |
| dc.description.abstract | Chalconesbelongto important classofflavonoid compounds.Theyhavealsobeen reported to have anticancer, antimicrobial, antifungal, antioxidant, and cytotoxic activities. In this research, an analogous chalcone of(E)-3-(4clorophenyl)-1-(3’,4’ dimetoxyphenyl) prop- 2-en-1-on wassynthesized using microwaveiradiation and natriumhidroxideas catalyst. Thecompound showed a goodyield,and then was characterizedbyUVspectroscopy,IR, 1 H-NMR,andMassSpectroscopy.Its toxicity hasbeenidentified usingBrineShrimpLethalityTest(BSLT) methodonArtemia salina Leach. The result showed that it had a good toxicity activity with LC50=2.24µg/mLandpotentialasanticancer. | en_US |
| dc.description.sponsorship | Balatif, N., Zamri, A | en_US |
| dc.identifier.other | Rangga Dwijunanda Putra | |
| dc.identifier.uri | http://repository.unri.ac.id/xmlui/handle/123456789/5936 | |
| dc.language.iso | other | en_US |
| dc.subject | 3’,4’-dimetoxyacetophenone | en_US |
| dc.subject | BSLT | en_US |
| dc.subject | chalcones | en_US |
| dc.subject | toxicity | en_US |
| dc.title | SINTESISDANUJITOKSISITASSENYAWAANALOG 3’,4’-DIMETOKSIKALKON | en_US |
| dc.type | Other | en_US |