Browsing by Author "Nasution, Musyirna Rahmah"

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    UJI INFUSA BAWANG PUTIH, DAUN MANGKOKAN DAN TEMU GIRING SEBAGAI INHIBITOR ENZIM α-AMILASE
    (2016-10-19) Elpilasari, Sisca; Devi, Silvera; Nasution, Musyirna Rahmah
    The objective of this study were to determine in-vitro α-amylase inhibitory activities of aqueous extracts (infusa) from medicinal plants, i.e., garlic (Allium sativum L.), mangkokan leaves (Nothopanax scutellarium Merr.), and temu giring (Curcuma heyneana Val. & V) in their fresh and dried samples. Inhibition of α-amylase enzymes was determined by DNS method, and the absorbance was measured by microplate reader. Acarbose was used as positive control. The results showed that all samples were potential inhibitors for α-amylase. Activities of 4 extracts were not significantly different from acarbose (93.89 + 0.02), i.e., infusa of mangkokan fresh leaves (88.62 + 5.04); infusa of mangkokan dried leaves (91.64 + 1.17); infusa of fresh temu giring (76.05 + 11.84); and infusa of dried temu giring (90.46 + 2.67).
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    UJI INFUSA DAUN ASAM JAWA, HERBA BENALU API DAN HERBA PUTRI MALU SEBAGAI INHIBITOR ENZIM α-GLUKOSIDASE
    (2016-10-12) Jannah, Ninuk Rodhiatul; Devi, Silvera; Nasution, Musyirna Rahmah
    Diabetes mellitus is a metabolic disorder that has become a serious problem in the world, especially type 2 diabetes mallitus. Prevention of type 2 diabetes mellitus could be done by inhibiting α-glucosidase enzyme in order to decrease the blood glucose. The objectives of this study were to determine in-vitro α-glucosidase inhibitory activities of aqueous extracts (infusa) from medicinal plants, tamarind leaves (Tamarindus Indica L), parasite flame herb (Scurrul sp) and putri malu herb (Mimosa pudica L) in fresh samples and dried samples. Inhibition of α-glucosidase enzymes was determined by p-NPG substrate, and the absorbance was measured by microplate reader. Acarbose was used as positive control. The results showed that all samples were potential inhibitors for α-glucosidase. Activites of 3 extracts were not significantly different from acarbose (97.99 + 0,19) i.e., infusa of tamarind dried leaves (99.10 + 0.36); infusa of parasite flame fress herb (97.96 + 0.85) and infusa of putri malu fresh herb (98.64 + 1.25).