Biology

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Browsing Biology by Author "Anisa, Fara"

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    UJI TOKSISITAS DAN AKTIVITAS ANTIOKSIDAN TIGA JENIS GULMA POTENSIAL SEBAGAI TUMBUHAN OBAT DENGAN METODE BSLT (Brine Shrimp Lethality Test) DAN DPPH (2,2-difenil-1- pikrilhidrazil)
    (Elfitra, 2023-04) Anisa, Fara; Fitmawati, Fitmawati
    The three potential weeds, Asystasia gangetica, Artemisia vulgaris and Ruellia tuberosa, tend to be ignored because they are considered as plants that live in unwanted or disturbing places. Weed plants contain antioxidant compounds as such useful for environment change adapt. However, phytochemical characterization data as basic data in the development of this plant as a medicinal material is not yet available. Therefore, it is necessary to conduct research on toxicity tests and antioxidant activity on three weeds using methanol solvent. The study was conducted in vivo with BSLT method using Artemia salina larvae to obtain half-maximal lethality concentration (LC50) and with DPPH method using microplate reader to obtain Inhibition concentration (IC50). The results showed that the leaf and stem extracts of Artemisia vulgaris showed the character of cytotoxic ability with LC50 values of 0.0342 ppm respectively and the leaf and stem extracts of Ruellia tuberosa LC50 values of 0.0584 ppm while extracts of leaves and stems of mixed Asystasia gangetica showed low toxic and non-toxic character 336.584 ppm. The results of testing the antioxidant activity of the three weeds Asystasia gangetica are 110.9 ppm, IC50 values in mixed leaf and stem extracts of Artemisia vulgaris are 148 ppm. The IC50 values of leaf and stem extracts of Ruellia tuberosa are 17 ppm, indicating that the three weeds no potential as antioxidant activity.