SYNTHESIS AND STRUCTURAL STUDIES OF N-(HALOGENOCARBONOYL)-N'-(ARYL)THIOUREA

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dc.contributor.authorAbosadiya, Hamza M
dc.contributor.authorHasbullah, Siti Aishah
dc.contributor.authorYamin, Bohari M
dc.date.accessioned2014-05-21T03:31:11Z
dc.date.available2014-05-21T03:31:11Z
dc.date.issued2014-05-21
dc.description.abstractThe number of structure of carbonoylarylthiourea derivatives is increasing because of their potential in biological properties. The structural informations are important for the structureactivity relationship studies or rational drug design work. However, the thioureas containing halogen in the carbonoyl fragment is still very scarce. N-(3-chloropropionyl)-N'-(2- methylphenyl)thiourea(I) and N-(3-chloropropionyl)-N'-(4-methylphenyl)thiourea(II) were synthesized and characterized by FTIR and NMR spectroscopic techniques. The compound (I) was obtained as twinned crystal. The X-ray study showed that the asymmetric unit consists two independent molecules. The trans–cis configuration of the chloropropionyl and methyl phenyl groups respectively, against the thiono about their C-N bonds is maintaineden_US
dc.description.sponsorshipSeminar UR-UKM ke-7 2012en_US
dc.identifier.isbn978-602-18936-0-9
dc.identifier.otherwahyu sari yeni
dc.identifier.urihttp://repository.unri.ac.id/xmlui/handle/123456789/6265
dc.language.isoenen_US
dc.subjectthioureaen_US
dc.subject3-chloropropionylchlorideen_US
dc.subjectSingle-Crystal X-ray Studyen_US
dc.titleSYNTHESIS AND STRUCTURAL STUDIES OF N-(HALOGENOCARBONOYL)-N'-(ARYL)THIOUREAen_US
dc.typeUR-Proceedingsen_US

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