EFEK ANTIPIRETIK EKSTRAK ETANOL AKAR ILALANG (Imperata cylindrical (L.) beauv.) PADA MENCIT JANTAN (Mus musculus) YANG DI INDUKSI VAKSIN DPT
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Date
2013-02-19
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Abstract
Ilalang root is one of traditional medicine that often being used by citizen of
Indonesia to cure fever, cough, as diuretics and etc. The purpose of this research is to prove
the effect of antipyretic of Etanol extract of Ilalang root to male mice which are induced by
DPT vaccine. Twenty five of Male mices are separated into 5 groups, they are negative
control group which is given Aquades 0,3ml/20grbb, positive control which is given
paracetamol 6 mg/20grbb and a group which is given etanol extract of Ilalang root dosed
100%, 50%, 25%. Taking the temperature of mice’s rectals was done before and after being
induced by DPT vaccine at intervals 0, 1, 2, 4, 8, 16, 32 hours. At time of 12 was given
action. Antipyretic is successful if the mice’s rectals temperature are the same or higher than
the rectal’s temperature of positive control group. The result of this research shows that
ilalang root give higher antipyretic effect than paracetamol effect. The conclusion of this
research is etanol extract of ilalang root has antipyretic effect.
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Etanol extract of Ilalang root (Imperata cylindrical (L.) beauv.),, antipyretic, DPT vaccine, mice’s rectal temperature