ISOLASI DAN UJI TOKSISITAS EKSTRAK ETIL ASETAT DAUN Nerium oleander

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dc.contributor.authorFitria, Nelda
dc.contributor.authorTeruna, Hilwan Yuda
dc.contributor.authorEryanti, Yum
dc.date.accessioned2016-05-10T03:15:23Z
dc.date.available2016-05-10T03:15:23Z
dc.date.issued2016-05-10
dc.description.abstractThe isolation of Nerium oleander was carried out by maceration method using n-hexane and ethyl acetate. The ethyl acetate extract of N. oleander was fractionated by Vacuum Liquid Chromatography (VLC). The fractions with vial number 6 to 9 (Fga) from VLC was separated by column chromatography. The fractions with vial number 6 to 23 (Fgb) from column chromatography was separated by column chromatography. The fractions with vial number 66 to 69 (Fgc) from the second column chromatography was characterized using Ultraviolet-Visible (UV-Vis) and Fourier Transform InfraRed (FT-IR) methods. The toxicity of extract and fraction have been determined by using Brine Shrimp Lethality Test (BSLT) methods. The toxicity result showed that the ethyl acetate extract and fractions of VLC (F4, F5, Fga, F10, F11) have LC50 < 1000 ppm. It showed that extracts and fractions were toxic. However, the toxicity result showed that the fractions of VLC (F1, F2, F3) and Fgc have LC50 > 1000 ppm.en_US
dc.description.sponsorshipFakultas Matematika dan Ilmu Pengetahuan Alam Universitas Riauen_US
dc.identifier.issnwahyu sari yeni
dc.identifier.urihttp://repository.unri.ac.id/xmlui/handle/123456789/8361
dc.language.isoenen_US
dc.subjectNerium oleanderen_US
dc.subjectBSLTen_US
dc.subjecttoxicity assayen_US
dc.titleISOLASI DAN UJI TOKSISITAS EKSTRAK ETIL ASETAT DAUN Nerium oleanderen_US
dc.typestudent Paper Post Degreeen_US

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