SINTESIS SENYAWA 4-(1-(4-FLUOROFENIL)-5-(3-METOKSIFENIL)- 4,5-DIHIDRO-1H-PIRAZOL-3-IL) FENOL
dc.contributor.author | Kurniati, Maya | |
dc.contributor.author | Jasril, Jasril | |
dc.date.accessioned | 2025-01-22T03:39:48Z | |
dc.date.available | 2025-01-22T03:39:48Z | |
dc.date.issued | 2024-01 | |
dc.description.abstract | Pyrazoline has two nitrogen atoms adjacent to each other in its ring and possess only one endocyclic double bond. The pyrazoline compound 4-(1-(4-Fluorophenyl)-5-(3- Methoxyphenyl)-4,5-Dihydro-1H-Pirazol-3-yl) phenol and named as P3OME-4OH-4F has been successfully synthesized through three stages reaction. The first stage is the formation of the chalcone compound through the Claisen-Schmidt condensation reaction with a yield of 54%, the second stage is the formation of the hydrazine compound through diazotation and reduction reactions with a yield of 84% and the final stage is the formation of the P3OME-4OH-4F compound through a cyclization reaction with a yield obtained of 52%. The purity of the compound was tested by measuring the melting point, TLC and HPLC analysis. The structure of the P3OME-4OH-4F compound was confirmed by characterization using UV spectroscopy and FTIR. | |
dc.description.sponsorship | Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Riau | |
dc.identifier.citation | Perpustakaan | |
dc.identifier.other | Elfitra | |
dc.identifier.uri | https://repository.unri.ac.id/handle/123456789/11542 | |
dc.language.iso | en | |
dc.publisher | Elfitra | |
dc.subject | chalcone | |
dc.subject | pyrazoline | |
dc.subject | spectroscopy | |
dc.title | SINTESIS SENYAWA 4-(1-(4-FLUOROFENIL)-5-(3-METOKSIFENIL)- 4,5-DIHIDRO-1H-PIRAZOL-3-IL) FENOL | |
dc.type | Article |