SINTESIS DAN UJI ANTIBAKTERI SENYAWA (3E,5E)-3,5-BIS (4-HIDROKSIBENZILIDIN)PIPERIDIN-4-ON

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dc.contributor.authorSari, Tri Endah Tresna
dc.contributor.authorEryanti, Yum
dc.contributor.authorYuharmen
dc.contributor.authorZamri, Adel
dc.date.accessioned2014-03-27T06:45:31Z
dc.date.available2014-03-27T06:45:31Z
dc.date.issued2014-03-27
dc.description.abstractCurcumin is a colouring agent of Curcuma longa L. Beside the use of it as natural colourant, curcumin has biological activities such as antibacterial. In this research, curcumin analog compound of (3E,5E)-3,5-bis(4-hydroxybenzylidene)piperidin-4-one was synthesized with an acid catalyst (SOCl2) and the rendement obtained was 53.49 %. The purity of the compound has been tested using TLC, melting point test, and analytical HPLC. The identification of curcumin analogues was done using UV, IR, MS, 1 H NMR, and 13 C NMR. Antibacterial activity of the compound was identified by using disc diffusion method. The result showed that this analog of curcumin is inactive as an antibacterial agent.en_US
dc.description.sponsorshipEryanti, Yum., Yuharmen., Zamri, Adelen_US
dc.identifier.otherRangga Dwijunanda Putra
dc.identifier.urihttp://repository.unri.ac.id/xmlui/handle/123456789/5947
dc.language.isootheren_US
dc.subjectAntibacterial activityen_US
dc.subjectCurcuminen_US
dc.subjectSynthesisen_US
dc.titleSINTESIS DAN UJI ANTIBAKTERI SENYAWA (3E,5E)-3,5-BIS (4-HIDROKSIBENZILIDIN)PIPERIDIN-4-ONen_US
dc.typeOtheren_US

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