ISOLASI DAN UJI TOKSISITAS EKSTRAK n-HEKSANA DARI BENALU JENGKOL Scurrula ferrugimea Danser

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dc.contributor.authorRamadhita, Yovani Kinanti
dc.contributor.supervisorYuharmen, Yuharmen
dc.date.accessioned2024-02-01T03:18:52Z
dc.date.available2024-02-01T03:18:52Z
dc.date.issued2023-09
dc.description.abstractScurrula ferruginea Danser is a semi-woody plant from the santalales family and the Loranthaceae family. This plant is considered detrimental because it is a parasite on other plants, but currently S. ferruginea has a lot of potential as a traditional medicine. This research aims to isolate secondary metabolite compounds, characterize the compounds, and analyze the toxicity test of the n-hexane extract of the S. ferruginea plant using the brine shrimp lethality test (BSLT) method. The extraction process was carried out using the maceration method with methanol solvent followed by a partition process using n-hexane and ethyl acetate solvents to obtain a thick n-hexane extract. Separation of components in the extract was carried out using vacuum liquid chromatography (VLC) and column chromatography methods. Fraction 2 from the results of column chromatography separation in the form of crystals coded SFH-F2 has a melting point of 134-136°C. Characterization using FTIR was obtained at wavenumber 3300 cm-1 (OH), 1451 cm-1 (CH2), 1380 cm-1 (CH3), 1189 cm-1 (CN), dan 1043 cm-1 and 1036 cm-1 (CO). Characterization using UV-Vis did not show any absorption. Based on the characterization results, the compound SFH-F2 is a terpenoid group. The results of toxicity testing of nhexane extract using the BSLT method obtained an LC50 value > 1000 ppm. These results indicate that the n-hexane extract of the S. ferruginea plant is non-toxic.en_US
dc.description.sponsorshipFakultasMatematika dan Ilmu Pengetahuan Alamen_US
dc.identifier.citationPerpustakaanen_US
dc.identifier.otherElfitra
dc.identifier.urihttps://repository.unri.ac.id/handle/123456789/11274
dc.language.isoenen_US
dc.publisherElfitraen_US
dc.subjectisolationen_US
dc.subjectcharacterizationen_US
dc.subjecttoxicityen_US
dc.titleISOLASI DAN UJI TOKSISITAS EKSTRAK n-HEKSANA DARI BENALU JENGKOL Scurrula ferrugimea Danseren_US
dc.typeArticleen_US

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