SINTESISDANUJITOKSISITASANALOG3’-BROMOKALKON
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Date
2014-03-27
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Abstract
Chalconeof1-(3’-Bromofenil)-3-(4’-Klorofenil)-2 propen-1-on has beensynthesized from3’-bromoasetofenonbystirrermethodandevaluatedfor its toxicity activity. 1-(3’-Bromofenil)-3-(4’-Klorofenil)-2-propen1-onshowedagoodyield, andthen it was characterizedusingUVspectroscopy, IR and 1
H-NMR. Its toxicity activityhasbeen identified usingBrineShrimpLethalityTest(BSLT)againstlarvae ofArtemiasalina Leach. The toxicity value of 1-(3’-Bromofenil)-3-(4’-Klorofenil)-2-propen-1-on
obtainedwas1,03mg/ mL. It indicated that the chalconehadagoodtoxicity and potentialasanticancer.
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Keywords
3’-bromochalcone, BrineShrimpLethalityTest, toxicity