Abstract:
The three potential weeds, Asystasia gangetica, Artemisia vulgaris and
Ruellia tuberosa, tend to be ignored because they are considered as plants that live
in unwanted or disturbing places. Weed plants contain antioxidant compounds as
such useful for environment change adapt. However, phytochemical
characterization data as basic data in the development of this plant as a medicinal
material is not yet available. Therefore, it is necessary to conduct research on
toxicity tests and antioxidant activity on three weeds using methanol solvent. The
study was conducted in vivo with BSLT method using Artemia salina larvae to
obtain half-maximal lethality concentration (LC50) and with DPPH method using
microplate reader to obtain Inhibition concentration (IC50). The results showed
that the leaf and stem extracts of Artemisia vulgaris showed the character of
cytotoxic ability with LC50 values of 0.0342 ppm respectively and the leaf and
stem extracts of Ruellia tuberosa LC50 values of 0.0584 ppm while extracts of
leaves and stems of mixed Asystasia gangetica showed low toxic and non-toxic
character 336.584 ppm. The results of testing the antioxidant activity of the three
weeds Asystasia gangetica are 110.9 ppm, IC50 values in mixed leaf and stem
extracts of Artemisia vulgaris are 148 ppm. The IC50 values of leaf and stem
extracts of Ruellia tuberosa are 17 ppm, indicating that the three weeds no
potential as antioxidant activity.
