UJI PENGHAMBATAN α-GLUKOSIDASE DARI EKSTRAK ETIL ASETAT TUMBUHAN PAKU Pyrrosia lanceolata

Abstract

The epiphytic plant Pyrrosia lanceolata belongs to the Polypodiaceae family. Studies on P. lanceolata are still under-reported, especially their bioactivity, whereas P. petiolosa, P. sheareri and P. lingua have been studied for the isolation of secondary metabolites and their bioactivity as anti-inflammatory and anti-oxidant. The result showed percentage inhibition of α-glucosidase methanol extract was 32.25%, n-hexane 19.15%, dichloromethane 10.52%, ethyl acetate 72.79% and for acarbose 99.79%. Based on percentage inhibition values obtained ethyl acetate extract has better activity than extracts methanol, n-hexane and dichloromethane in inhibiting α-glucosidase but less well than the positive control acarbose.