Aktivitas Antibakteri Peptaibol Produksi Gliocladium sp T.N.C73
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Date
2015-07-04
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Abstract
Peptaibols are a unique class of peptides. They are characterized by
molecular weights of 500- 2200 Da, a high number of non-proteinogenic,
a,adialkylated a-amino acids like isovaline (Iva) and a-aminoisobutyric acid (Aib), an
acetylated N-terminus, and an amino alcohol, mostly phenylalaninol, at the Cterminal
end, which is lacking in the peptaibiotics. The name G peptaibol H
originates from parts of the words peptide, Aib, and amino alcohol. Although
peptaibols are not only produced by Trichoderma, most of the peptaibols known
today have been found in this genus like Gliocladium sp. In metabolite production
and extraction from Gliocladium sp. T.N.C73, it was harvested a few mycelium.
TLC and detection of antibiotic compounds. MeOH extracts of Gliocladium sp
T.N.C73 mycelium, were investigated for the presence of secondary metabolites
including peptaibols by TLC. The separated compoimds, indentified as red spot. In
this experiments, don't have red spot. Probability, dilute over sample.
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Keywords
peptaibol, mycelium, Gliocladium sp