UJI POTENSI SENYAWA FENOLIK DAUN TANAMAN SEMBUNG RAMBAT (Mikania micrantha Kunth) SEBAGAI INHIBITOR α-AMILASE

Abstract

The α-amylase is an enzyme found in the human digestive process that hydrolyzes starch into maltose and maltose is then hydrolyzed by maltase into glucose. High levels of glucose in the blood can be reduced by inhibiting the activity of α-amylase. The leaves of the sembung rambat plant (Mikania micrantha Kunth) belonging to the Asteraceae family are predicted to contain phenolic active compounds that can act as α-amylase inhibitors. Phenolics from the leaves of this plant were extracted with methanol, ethyl acetate, and hydro-methanol as solvents. Furthermore, the levels of these active compounds and their inhibitory power to α-amylase activity were determined.