Browsing by Author "Azizah, Nur"

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    KARAKTERISASI TUMBUHAN SUNGKAI (Peronema canescens Jack.) ASAL TIGA LOKASI DI PROVINSI BERDASARKAN METODE LC-MS
    (Elfitra, 2023-04) Azizah, Nur; Fitmawati, Fitmawati
    Sungkai (Peronema canescens Jack.) belongs to the Lamiaceae family which has various active compounds function as antipyretic to antioxidant so it is widely used as medicine. Sungkai samples were taken from three locations in Riau Province, namely Kuantan Singingi, Pekanbaru and Siak. The purpose of this study was to characterize and determine the types of phytochemical compounds contained in sungkai plants and to differentiate sungkai from three locations in Riau Province using the LC-MS method. Sampling was carried out using a survey method. Samples were analyzed using the LC-MS system. Chromatogram was analyzed using the MassLynx program to obtain the compounds contained in the sample. Determination of compound names was based on the Chemspider database and compound groups based on PubChem. Grouping of the three origins of Sungkai was carried out using the NTSYSpc2.02 program. There were 296 metabolite compounds which were used for grouping sungkai from trhee regions. Results showed that ekstract leaf sungkai from three locations contain compounds belonging to the class of flavonoids, phenolics, alkaloids, amino acids, aromatic compounds, sesquiterpenoids, carboxylic acids, essential oils, medium-chain fatty acids and nucleic acid. Three sungkai from three locations were divided into two groups with similarity coefficient values ranging from 31% -48. Group I is from Kuantan Singingi and group II is from Pekanbaru and Siak. The metabolites found in this study are expected to be useful as basic data in the field of phytopharmaca and medicine.
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    SINTESIS DAN UJI AKTIVITAS ANTIBAKTERI KALKON INTI NAFTALEN DARI ASETILNAFTALEN DAN 4-NITROBENZALDEHID
    (2016-10-19) Azizah, Nur; Jasril; Zamri, Adel
    Chalcon as synthetic compound or natural product had important biology activity. Biology activity of chalcone due to α, β unsaturated system. This research about synthesized a chalcone compound (E)-3-(4-nitrophenil)-1-(naphtalene-1-il)prop-2-en-1-on(AZ1) via aldol condensation reaction by using acetylnaphthalene and 4-nitrobenzaldehyde as precursor. The compound used KOH 6 N as catalyst. AZ had yields 73,02 % and characterized by UV spectroscopy, IR, 1H-NMR and 13C-NMR. The antibacterial activity determined by agar diffusion method in concentration 10 μg/disk and 30 μg/disk. The antibacteria test used Staphylococcus aureus and Bacillus subtilis (Gram positive bacteria), Escherichia coli and Salmonella enteritidis (Gram negative bakteria) as bacteria test