Abstract:
A total of 76.45 g viscous water extract has been isolated by maceration of powdered
yellow watermelon (Citrullus vulgaris) rind (1300 g). The extract was then separated by
column chromatography which produced 5 fractions. Antimicrobial assay was
performed by the agar diffusion method against Gram-negative bacteria (Escherichia
coli), Gram-positive (Staphylococcus aureus) and fungus Candida albicans. The results
showed that both extract and fractions were active in inhibiting the growth of both
bacteria, but not for the growth of C. albicans. The best activity was shown by F2 (10
mm) againts Gram-negative bacteria (Escherichia coli) and F3 (8 mm) againts Grampositive
bacteria (Staphylococcus aureus).
