Abstract:
Urolithiasis is a dangerous disease for human. The most common treatment to cure this disease is using medicinal plants as an alternative treatment. The aims of this research were to identify toxicity level of Stronbilanthes crispus served as antiurolithiasis agent using Brine Shrimp Lethality Test (BSLT) method and to determine LC50 of Stronbilanthes crispus extract treating to Artemia salina larvae. The study had been conducted from November 2014 to Februari 2015. In this research we used four ected which were with different extract concentration, i.e. control, 10 μg/ml, 100 μg/ml and 1000 μg/ml. Total Artemia salina larvae died after 24 hours treatment on each extract concentration medicinal plant were count. The toxicity was be analyzed using Probit analysis to determine LC50. The result of toxicity test indicated that leaf extract of Stronbilanthes crispus have lethal effect (LC50) to Artemia salina larvae at concentration of 234,42 μg/ml.