SINTESIS (E)-3-(4-FLUOROFENIL)-1-(NAFTALEN-1-IL)PROP-2-EN-1-ON DARI 1-ASETILNAFTALEN DAN 4-FLUOROBENZALDEHID

Abstract

Chalcone analogues has been synthesized by aldol condensation using stirring method with a base catalyst (KOH). Starting material that has been used was 1- acetylnaphthalene as ketone and 4-fluorobenzaldehyde as aldehyde. This compound were (E)-3-(4-flurophenyl)-1-(naphthalen-1-yl)prop-2-en-1-one. The purity of the product has been evaluated by TLC, melting point test, and HPLC analysis. The structures of the synthesized compound were confirmed by UV, FTIR, NMR, and MS analysis. Data of characterization showed that the compound obtained was based on target compound