Abstract:
Yellow root is a plant that belongs to Menispermaceae genus and widely used in
traditional medicine due to its antibacterial, anti-inflammatory and anti-diabetic
properties. One of the yellow root species that widely used in traditional medicine is
Arcangelisia flava isolated from Ranah Sungkai Village, XII Koto Kampar District,
Kampar Regency. This study aims to isolate secondary metabolites from the extract of
yellow root (A. flava) and determine their antifungal activity against the pathogenic
fungus Candida albicans. The antifungal activity test was carried out using the
microdilution method to determine the MIC (minimum inhibitory concentration) value
and the agar diffusion method to determine the MFC (minimum fungicidal
concentration) value. The test samples used were dicloromethane extracts with
concentrations of 1,000, 500, 250 μg/mL. The results of the antifungal test showed that
the dicloromethane extract had a MIC value of 250 μg/mL and MFC 250 μg/mL against
C. albicans.
