Abstract:
Peperomia pellucida is one of species belongs to Piperaceae family which is widely
distributed in Indonesia. This plant commonly is used as a traditional medicine by
various tribes in Indonesia. Several species of Peperomia are reported have antidiabetic,
antioxidant, antibacterial, and antiinflammatory. However, the antidiabetic activity from
this plant rarely investigated. The extract and the pure compounds were tested for
antidiabetic activity by α-glucosidase inhibitor assay. The inhibitory activity was
assayed using microplate reader. The results with inhibition persentage values 0,832 %
for n-hexane extract, -0,355 % for PP-H-03 and -1,102 % for PP-H-08. Based from the
data the extract and isolated compound showing weak antidiabetic activity compared to
positive control of acarbose.
