FRAKSINASI KROMATOGRAFI KOLOM METABOLIT SEKUNDER DARI Penicillium sp. LBKURCC34 BERPOTENSI ANTIBAKTERI Escherichia coli

Abstract

Penicillium sp. LBKURCC34 is a a producer of secondary metabolite compounds that has several biological activities such as antibacteria and is known as of antibiotics. In this study, Penicillium sp. LBKURCC34 was tested as a producer of antibacterial active compounds against E. coli. Ethyl acetate crude extract from 14 days fermentation of Penicillium sp. LBKURCC34 was tested by TLC by several ration of eluants, such as ethyl acetate: n-hexane (1:1; 3:2; and 7:3) with UV light (254 and 366 nm). Column chromatography separation produced 13 fractions with some of the fractions have antie. coli.