UJI DAYA HAMBAT ANTIFUNGI MINYAK ESSENSIAL TEA TREE (Melalueca alternifolia) TERHADAP PERTUMBUHAN Trichophyton mentagrophytes ATCC R4608300 DAN Microsporum canis

Abstract

Dermatophytes are the major cause of superficial mycosis that are ability to invade keratinize tissue and cause dermatophytosis, the most common human and animals contagious fungal disease. Trichophyton mentagrophytesATCC R4608300 and Microsporum canis are among the fungi causing dermatophytosis. Natural product with antifungal activity become necessary to overcome difficulties on treatment of these infections. This study aimed to determine the ability of tea tree essential oil to inhibit dermatophyte fungi. The antifungal screening was performed by well diffusion method. The result showed tea tree essential oil concentration (1%, 3%, 5%) were weak categorization against T. mentagrophytes ATCC R4608300 and M. canis while the 0.1% concentration of tea tree essential oil did not show any inhibition. Ketoconazole as a positive control had moderate inhibition against the fungi.