Nurchayati, SofianaRahmalia, Siti2015-06-202015-06-202015-06-202406-9175wahyu sari yenihttp://repository.unri.ac.id/xmlui/handle/123456789/7112Quality of Life (QoL) has become an important clinical outcome to measure the effectiveness of interventions on patients with chronic renal failure (CRF) who are undergoing regular hemodialysis (HD), which hemodialysis adequacy is an important predictor of QoL. The aim of this study was to determine the relationship between hemodialysis adequacy and QoL in patients with CRF who receive HD therapy. The purposive sampling method was used to select 43 respondents who undergoing regular HD twice a week. The formula Kt / V was used to measure hemodialysis adequacy while QoL was assessed by using a WHOQoL questionnaire. The age range of the respondents was 25 to 75 years old, male 55.8%, female 44.2%, duration for each HD therapy (3 hours 4.6%, 4 hours 69.8% and 5 hours 25.6%). The research findings have shown that only 25.6% patients met with the HD adequacy requirement, whereas 48.8% respondents had poor QoL and 51.2 % of them had a good in QoL. Statistical analysis using chi square has shown that there was no significant relationship between hemodialysis adequacy and QoL (p value = 0.79). Achievement of high HD adequacy is needed to improve in order to enhance QoL. Further research needs to determine the strength of the disease profiles and clinical characteristics in order to confound QoL in this patient group.enhemodialysis adequacyquality of lifeUR-Proceedings