Azizah, NurJasrilZamri, Adel2016-10-192016-10-192016-10-19wahyu sari yenihttp://repository.unri.ac.id/xmlui/handle/123456789/8708Chalcon as synthetic compound or natural product had important biology activity. Biology activity of chalcone due to α, β unsaturated system. This research about synthesized a chalcone compound (E)-3-(4-nitrophenil)-1-(naphtalene-1-il)prop-2-en-1-on(AZ1) via aldol condensation reaction by using acetylnaphthalene and 4-nitrobenzaldehyde as precursor. The compound used KOH 6 N as catalyst. AZ had yields 73,02 % and characterized by UV spectroscopy, IR, 1H-NMR and 13C-NMR. The antibacterial activity determined by agar diffusion method in concentration 10 μg/disk and 30 μg/disk. The antibacteria test used Staphylococcus aureus and Bacillus subtilis (Gram positive bacteria), Escherichia coli and Salmonella enteritidis (Gram negative bakteria) as bacteria testenAldol condensationantibacteria activitychalconeSINTESIS DAN UJI AKTIVITAS ANTIBAKTERI KALKON INTI NAFTALEN DARI ASETILNAFTALEN DAN 4-NITROBENZALDEHIDstudent Paper Post Degree