Shinta, Dewi YudianaSonata, Herix2019-01-092019-01-092019-01-10978-979-792-865-0wahyu sari yenihttp://repository.unri.ac.id/handle/123456789/9551Indonesia is one of the agricultural countries that use pesticides high enough to control various pests that can reduce the population of plant pest organisms (OPT). Cholinesterase in the blood will bind, because in blood it is generally used as a parameter of pesticide poisoning. Cholinesterase is also synthesized in the liver or liver, blood plasma, and red blood cells. Leukocytes in the blood of farmers who experience pesticide poisoning will increase. The purpose of this study was to analyze the relationship between the number of leukocytes and cholinesterase cases of poisoning in farmers. This study uses a blood sample of farmers as many as 20 people. The results showed that the correlation test of Pearson test results showed p = 0.563 and r = 0.137. This means that there is no significant relationship between the number of leukocytes and cholinesterase cases of pesticide poisoning in farmers with very weak and insignificant correlation strengths. The use of pesticides to control plant pests contains the risk of accidents in humans in the form of chronic / acute poisoning and / or death. The severity of the level of poisoning is related to the level of inhibition of cholinesterase in the blood.encholinesteraseleukocytespesticidesArticle