Abstract:
Potential actinomycetes in producing antibacterial compound has been widely
studied. However, not so many information about antibacterial compound
produced by local isolates actinomycetes from Riau despite its high diversity. The
aim of this research is to determine potential of actinomycetes from Rimbo
Panjang Peat, Kampar, Riau in producing antibacterial compounds against
S. aureus. Agar disc method was used to test the antibacterial activity by
measuring the inhibition zone. Furthermore, antibacterial compounds produced by
isolated filtrate of actinomycetes, following five day fermentation, were tested
using paper disc method. The result showed that 13 of 40 isolates which were
tested using agar disc method had antibacterial activity against S. aureus with the
highest inhibition zone was 18,45 mm (isolates KN 5.4). Meanwhile, only 6 of 13
isolates filtrate which were tested using paper disc method showed antibacterial
activity with the highest inhibition zone of 16,16 mm (KN 5.4).
