Abstract:
Penicillium sp. LBKURCC34 is a a producer of secondary metabolite compounds that
has several biological activities such as antibacteria and is known as of antibiotics. In
this study, Penicillium sp. LBKURCC34 was tested as a producer of antibacterial active
compounds against E. coli. Ethyl acetate crude extract from 14 days fermentation of
Penicillium sp. LBKURCC34 was tested by TLC by several ration of eluants, such as
ethyl acetate: n-hexane (1:1; 3:2; and 7:3) with UV light (254 and 366 nm). Column
chromatography separation produced 13 fractions with some of the fractions have antie.
coli.