SINTESIS (E)-3-(4-FLUOROFENIL)-1-(NAFTALEN-1-IL)PROP-2-EN-1-ON DARI 1-ASETILNAFTALEN DAN 4-FLUOROBENZALDEHID
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Date
2014-03-27
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Abstract
Chalcone analogues has been synthesized by aldol condensation using stirring method with a base catalyst (KOH). Starting material that has been used was 1- acetylnaphthalene as ketone and 4-fluorobenzaldehyde as aldehyde. This compound
were (E)-3-(4-flurophenyl)-1-(naphthalen-1-yl)prop-2-en-1-one. The purity of the product has been evaluated by TLC, melting point test, and HPLC analysis. The
structures of the synthesized compound were confirmed by UV, FTIR, NMR, and MS
analysis. Data of characterization showed that the compound obtained was based on
target compound
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Keywords
aldol condensation, chalcone