Abstract:
Many kinds of plant species grow in Indonesia. One of them is Mahang (Macaranga
triloba (Muell.) Arg.). Mahang (Macaranga triloba (Muell.) Arg.) leaf are often used as
traditional medicine. The aims of this study were to find the activity of bacterias using
4 extraction methods and to find the most effective extraction method and concentration
in inhibition the bacteria growth againts E. coli and S. typhi. The extraction which had
been done by maceration method with methanol dissolver, boiling dry leaf, grinding
leaf, boiling fresh leaf. The testing activity was done using paper disk and agar well by extract concentration 100%, 75%, 50%, 25% and 10%. The result of this research
showed that of the most effective extraction method and concentration in producing
inhibition zone were methanol in concentration of 100%, both E. coli and S. typhi, that is 15,43±2,19 mm and 20,67±1,14 mm
